Primary Supervisor: A/Prof Sokcheon Pak
Location: Bathurst/Orange
Keywords: Orthostatic Intolerance; Long COVID; HSOP; Dysautonomia; Tachycardia; Brain Fog.
Project availability: Available currently
Synopsis:
This observational study aims to assess the effects of plasmalogens on the cognitive function in children and adolescents with Postural Orthostatic Tachycardia Syndrome (POTS).
POTS is a form of orthostatic intolerance and a chronic disorder of the autonomic nervous system. Patients with POTS frequently experience sinus tachycardia with a sustained increase in heart rate (HR) of more than 30 beats per minute (bpm) upon standing (≥ 40 bpm in individuals under 19 years old), while maintaining normal blood pressure (Vernino et al., 2021). Such sinus tachycardia is also not caused by any other underlying medical conditions, such as anaemia, hyperthyroidism, dehydration, pain, fever, or infections.
Participants (N = 12, aged 8–18 years) will consume a scallop oil plasmalogens supplement (HSOP) at a dose of 0.5 or 1 mg daily for 90 days. Serum plasmalogens level, cognitive function, heart rates, and quality of life will be assessed before and after the intervention. This pilot trial will provide preliminary findings to inform the potential use of plasmalogens supplementation in managing POTS.
Interested? Start the conversation here by contacting A/Prof Sokcheon Pak