Primary Supervisor: Dr David Leaver
Co-supervisors: Dr. Doaa Hanafy
Location: Wagga Wagga
Keywords: UTI, carbohydrates, biomimetics
Study Availability: Available until December 2027
Research Group: Medical Sciences
Synopsis:
Urinary tract infections (UTIs) are caused by gram-negative uropathogenic Escherichia coli (UPEC) and present a significant health burden for women with approximately 20 million cases reported annually. Approximately 20-40% of women treated with antibiotics will have at least one recurrence within 6 months of initial diagnosis which results in a loss of 2 billion dollars per year in the US alone. The main goal of this project is to develop novel antagonists of the mannose-binding type I pilus adhesin FimH, which is required to colonize the bladder epithelium during UTIs.
Interested? Start the conversation here by contacting Dr David Leaver