Primary Supervisor: Dr Ken Chinkwo
Location: Wagga Wagga
Keywords: cancer, chicken-egg, CAM assay, sorghum, antioxidants
Research Group: Food as Medicine (FAM) Research Group
Synopsis:
This project, led by Dr. Kenneth Chinkwo at Charles Sturt University, aims to revolutionize cancer study by developing a novel, cost-effective preclinical model using the Chicken Chorioallantoic Membrane (CAM) assay. By engrafting cancer cells such as colon, prostate, as well as canine osteosarcoma (OSA) cell lines onto the CAM, the research seeks to evaluate the therapeutic potential of polyphenolic compounds derived from sorghum and chickpeas, known for their potent antioxidant and anticancer properties.
This innovative approach addresses significant gaps in most cancers, including OSA treatments, but also offers a translational bridge to human oncology, as canine osteosarcoma closely mirrors its human counterpart. The project promises to provide foundational insights into tumor biology, angiogenesis, and metastasis while exploring natural therapeutic solutions with minimal toxicity. With a focus on reproducibility, ethical considerations, and real-time monitoring, this research has the potential to significantly advance both veterinary and human cancer treatment strategies, making it an exciting opportunity for students interested in cutting-edge cancer research and translational medicine.
ASBMB Biomolecular Horizon 2024 Poster
Interested? Start the conversation here by contacting Dr Kenneth Chinkwo